导师信息

孙朝阳

院系名称:附属同济医院

担任职务:

专业职称:教授

导师类别:硕士生导师

导师代码:

一级学科码:        一级学科名称:

二级学科码:       二级学科名称:

研究方向

肿瘤靶向治疗

所在科室

妇产科学

个人简介

主要从事肿瘤个体化靶向治疗的研究。近五年以第一作者或通讯作者发表SCI论文10篇,总影响因子80.282分,包括JNCI:Journal of National Cancer Insititue, Science Translational Medicine, Cancer Cell。

教育与工作经历

2003-2010:华中科技大学同济医学院临床医学7年制;
2010-2013:华中科技大学附属同济医院妇产科博士;
2013-2015:华中科技大学附属同济医院妇产科,住院医师及主治医生;
2015 -2018:美国MD Anderson Cancer Center博士后

已结题科研项目

青年科学基金项目: Dicer1调控PGC-1α导致卵巢癌线粒体相关性顺铂耐药的分子机制及靶向治疗研究

在研项目

同济医院青年英才II启动基金: 卵巢癌器官样培养及高通量药物筛选平台的建立及应用

指导的研究生获得奖励

代表学术论文

1. BRD4 inhibition is synthetic lethal with PARP inhibitors through the induction of homologous recombination deficiency. 201803, Cancer Cell. Chaoyang Sun*, Jun Yin, Yong Fang,Jian Chen, Kang Jin Jeong, Xiaohua Chen, Christopher P. Vellano1, Zhenlin Ju, Wei Zhao, Dong Zhang, Yiling Lu, FundaMeric-Bernstam, Timothy Yap, Maureen Hattersley, Mark O’Connor, Huawei Chen, Stephen Fawell, Shiaw-Yih Lin, Guang Peng, Gordon B. Mills
2. Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers. 201705, Science Translational Medicine. Chaoyang Sun*, Yong Fang, Jun Yin, Jian Chen, Zhenlin Ju, Dong Zhang, Xiaohua Chen, Christopher P. Vellano, Kang Jin Jeong, Patrick Kwok-Shing Ng, Agda Karina B. Eterovic, Neil H. Bhola, Yiling Lu, Shannon N. Westin, Jennifer R. Grandis, Shiaw-Yih Lin, Kenneth L. Scott, Guang Peng, Joan Brugge, Gordon B. Mills
3. miR-9 regulation of BRCA1 and ovarian cancer sensitivity to cisplatin and PARP inhibition. 201311, JNCI: Journal of the National Cancer Institute. Chaoyang Sun#, Na Li#, Zongyuan Yang, Bo O Zhou, Yang He, DanhuiWeng, Yong Fang, Peng Wu, Pingbo Chen, Xiaokui Yang, Ding Ma*, Jianfeng Zhou*, Gang Chen*
4. Safety of ovarian preservation in young patients with early-stage endometrial cancer: a retrospective study and meta-analysis. 201309, Fertility and Sterility. Chaoyang Sun#,Gang Chen#,Zongyuan Yang, Jie Jiang,Xingsheng Yang,Na Li,Bo Zhou,Tao Zhu,Juncheng Wei,DanhuiWeng,Ding Ma,Changyu Wang*, Beihua Kong*.
5. The role of BRCA status on the prognosis of patients with epithelial ovarian cancer: a systematic review of the literature with a meta-analysis. 201405, PLOS One. Chaoyang Sun#, Na Li#, Dong Ding#, DanhuiWeng, Li Meng, Gang Chen* , Ding Ma*

获奖情况

连续两年获得MDACC的 “The Diane Denson Tobola Fellowship in Ovarian Cancer”奖励

E-mail

suncydoctor@163.com

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